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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX1
All Species:
37.27
Human Site:
Y179
Identified Species:
74.55
UniProt:
Q9NRD9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD9
NP_787954.1
1551
177235
Y179
W
L
D
G
S
A
I
Y
G
S
S
H
S
W
S
Chimpanzee
Pan troglodytes
XP_001163196
1551
177072
Y179
W
L
D
G
S
A
I
Y
G
S
S
H
S
W
S
Rhesus Macaque
Macaca mulatta
XP_001111340
1551
176921
Y179
W
L
D
G
S
A
I
Y
G
S
S
H
S
W
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001092767
1551
177113
Y179
W
L
D
G
S
A
I
Y
G
S
S
H
S
W
S
Rat
Rattus norvegicus
Q8CIY2
1551
177179
Y179
W
L
D
G
S
A
I
Y
G
S
S
H
S
W
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
Y186
W
L
D
G
S
S
I
Y
G
S
S
H
S
W
S
Chicken
Gallus gallus
XP_425053
1523
173782
Y166
W
L
D
G
S
S
I
Y
G
P
S
H
S
W
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
G46
Y
P
A
Q
Y
M
D
G
V
Y
L
A
R
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
M166
S
E
A
W
L
N
A
M
R
S
F
H
N
G
T
Honey Bee
Apis mellifera
XP_624355
1492
172466
Y170
W
I
D
G
S
F
V
Y
S
S
S
E
A
W
A
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
Y176
W
I
D
G
S
F
I
Y
G
T
T
Q
P
W
V
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
Y261
W
F
D
G
G
L
V
Y
G
T
T
K
A
W
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.7
N.A.
N.A.
91
90.1
N.A.
73.9
65.1
N.A.
47.1
N.A.
39.9
40.3
34.3
41.6
Protein Similarity:
100
99.4
97.8
N.A.
N.A.
95
94.4
N.A.
84.4
78.4
N.A.
61.7
N.A.
58
60.2
55.9
59.3
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
86.6
N.A.
0
N.A.
13.3
53.3
53.3
40
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
93.3
N.A.
6.6
N.A.
26.6
80
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
42
9
0
0
0
0
9
17
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
84
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% E
% Phe:
0
9
0
0
0
17
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
84
9
0
0
9
75
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% H
% Ile:
0
17
0
0
0
0
67
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
59
0
0
9
9
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% R
% Ser:
9
0
0
0
75
17
0
0
9
67
67
0
59
0
59
% S
% Thr:
0
0
0
0
0
0
0
0
0
17
17
0
0
0
9
% T
% Val:
0
0
0
0
0
0
17
0
9
0
0
0
0
0
9
% V
% Trp:
84
0
0
9
0
0
0
0
0
0
0
0
0
84
0
% W
% Tyr:
9
0
0
0
9
0
0
84
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _